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Home - Products - Microbiology/Virology - CMV - GW 275175X

GW 275175X

CAS No. 217950-62-4

GW 275175X( GW275175X )

Catalog No. M13479 CAS No. 217950-62-4

GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GW 275175X
  • Note
    Research use only, not for human use.
  • Brief Description
    GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.
  • Description
    GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    GW275175X
  • Pathway
    Microbiology/Virology
  • Target
    CMV
  • Recptor
    CMV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    217950-62-4
  • Formula Weight
    398.034
  • Molecular Formula
    C12H11BrCl2N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-Bromo-5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92. 2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51.
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